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Since weight is lost by when the calorie intake is less than the calories used, most diet pills work either by reducing the calorie intake or increasing the metabolic rate so that calories are used up faster. Appetite suppressants are a category of diet pills which help in weight loss by helping the user reduce their food intake.

Some of the appetite suppressants work by either stimulating the production of neurotransmitters which make you feel full or suppressing the production of neurotransmitters which make you feel hungry. Other diet pills contain fiber, which absorb water and create a feeling of fullness which  reduces the hunger. All diet pills work best combined with proper diet and exercise.